Methyl Ester N-[6-(3-Cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamic Acid
DS28120313
CAS: 2146177-09-3
Molecular Formula: C16H17N5O2
Methyl Ester N-[6-(3-Cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamic Acid - Names and Identifiers
| Name | DS28120313 |
| Synonyms | DS28120313 Methyl Ester N-[6-(3-Cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamic Acid |
| CAS | 2146177-09-3 |
Methyl Ester N-[6-(3-Cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamic Acid - Physico-chemical Properties
| Molecular Formula | C16H17N5O2 |
| Molar Mass | 311.34 |
| Storage Condition | 2-8°C，密封，干燥 |
| In vivo study | DS28120313 (deliver orally; 30 mg/kg; 30 min before IL-6 administration) inhibits hepcidin production and reduces the blood hepcidin level in IL-6 induced acute inflammatory C57BL/6 mouse model. |
Methyl Ester N-[6-(3-Cyclopropyl-5-methyl-1H-pyrazol-4-yl)-1H-indazol-4-yl]carbamic Acid - Reference Information
| biological activity | DS28120313 is an oral hepcidin production inhibitor with an IC50 value of 0.093 μM. |
| target | IC50: 0.093 μM (hepcidin production) |
| in vivo research | DS28120313 (deliver orally; 30 mg/kg; 30 min before IL-6 administration) inhibits hepcidin production and reduces the blood hepcidin level in IL-6 induced acute inflammatory C57BL/6 mouse model. |
Last Update：2024-04-09 21:54:55
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